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→ PD-1/L1 Library

PD-1/L1 Library

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SDF PD-1/L1 Library 491 compounds
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PD-1 inhibitors and PD-L1 inhibitors are a group of checkpoint inhibitor anticancer drugs that block the activity of PD-1 and PDL1 immune checkpoint proteins present on the surface of cells. Immune checkpoint inhibitors are emerging as a front-line treatment for several types of cancer.

PD-1 and PD-L1 inhibitors act to inhibit the association of the programmed death-ligand 1 (PD-L1) with its receptor, programmed cell death protein 1 (PD-1). The interaction of these cell surface proteins is involved in the suppression of the immune system and occurs following infection to limit the killing of bystander host cells and prevent autoimmune disease. This immune checkpoint is also active in pregnancy, following tissue allografts, and in different types of cancer.
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TLR-8 ligands Library
 
pcs.
Anticancer Library
 
pcs.
Immunological Library
 
pcs.
Anti-Inflammatory Library
 
pcs.
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