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Custom chemistry. Chemistry FTE. Resynthesis.

Custom chemistry. Chemistry FTE. Resynthesis.

We are proud to offer our best expertise and 1st-class services to your organization

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ChemDiv constantly invests in design and production of novel patentable discovery chemistry.

Our team has extensive experience in addressing your synthetic chemistry, building block, medicinal chemistry and compound optimization needs. Our discovery chemistry expertise, combined with robust science and transparent business models, have allowed us to serve over 2,800 customers over the past 30 years, including pharmaceutical, cosmetics & agro companies, as well as biotechs and academia research groups.

Areas of expertise:

  • Discovery libraries design and synthesis
  •        ○ Clients’ scaffolds
           ○ ChemDiv propriety scaffolds (collection of over 30000 prevalidated templates)
  • Design and synthesis of unique building blocks
  • DEL building blocks
  • References compounds
  • H2L, SAR series generation
  • Synthetic route evaluation and development
  • Scale up (GMP standards)


Why choose ChemDiv:

  • Reliable source for novel chemistry and ideas
  • Over 300 novel scaffolds per year
  • Flexibility, transparent communication, regular reporting, excellent infrastructure
  • Fast turn-around time
  • FSS, FTE
  • Exclusive, semi-exclusive, non-exclusive
  • Science and business-focused professionals
  • Target consideration for design
  • Integration with discovery biology and pharmacology
  • Your custom selection criteria and flexible compounds library format
  • Excellent logistics
  • Proprietary collection of building blocks
  • Development and transfer of protocols and key intermediates
  • High-throughput H-NMR, LC/MC and HPLC-based purification
  • ChemDiv ensures resupply, resynthesis, immediate analogs selection, chemistry FTE, medchem FTE support for H2L.

FTE chemistry

ChemDiv offers fully integrated R&D Services, including FTE chemistry, to support pharmaceutical R&D projects. Over the past 29 years ChemDiv has delivered hundreds of leads, drug candidates and new drugs to our partners around the globe. Our FTE chemists bring deep expertise across the entire drug development pipeline. ChemDiv supports you in every step of the process to improve specific parameters of molecules and progress series from a hit to a lead and to a successful clinical candidate.

 

We offer cost-effective FTE chemistry services to our partners, including custom synthesis creation of focused and targeted libraries, in addition to traditional support. Working with us will allow you to access unique compounds exclusive to ChemDiv and our advantages:

  • Excellent track record for delivering multiple leads and clinical candidates for our customers and partners
  • ChemDiv’s proprietary scaffolds and building blocks
  • Top scientists with background in medicinal, computational and synthetic chemistry as well as in vitro and in vivo biology assist in progressing molecules from design to market launch
  • Well-earned international reputation in unique scaffold design and library synthesis
  • Advanced In silico / Computer-aided drug design (CADD)
  • A combination of SAR efforts through ADMET evaluation in scaffold design and early PK PD/Tox allows us to guide design of high quality lead candidates and back-ups
  • Seamless integration of all products and services upon customer request
  • Flexibility towards specific requirements of customer medicinal chemistry programs
  • Transparent communication, forward R&D planning, regular reporting and meetings


Chemistry FTE is an iterative process whereby new compounds are designed, synthesized and tested in various assays. The results are then analyzed and fed into the next round of designs. The more iterations with good quality chemistry and focused assay design, the faster the progress.


All these features make ChemDiv an excellent partner for various FTE chemistry projects:


  • Creation of targeted and focused libraries
  • Scaffold decoration using our proprietary scaffolds
  • Hit-to-lead optimization
  • Synthesis of building blocks and scaffolds up to scale-up

For more details on prices, time, or research specificity - please contact chemdiv@chemdiv.com or call us:

 


Custom chemistry and custom synthesis

ChemDiv offers fully integrated R&D Services, including custom chemistry and custom synthesis services, to support pharmaceutical R&D projects. Over the past 29 years ChemDiv has delivered hundreds of leads, drug candidates and new drugs to our partners around the globe. We are proud to offer our expertise to your projects.

 

Our customers can rely on us to be their one-stop cost-effective solution to their synthetic challenges. Our main fields of custom synthesis services are:

  • Discovery libraries design and synthesis
  • Design and synthesis of unique building blocks
  • DEL building blocks
  • References compounds
  • H2L, SAR series generation
  • Synthetic route evaluation and development
  • Scale up (GMP standards)
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