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DNA Encoded Libraries-CDI-Capabilities

DNA Encoded Libraries-CDI-Capabilities

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ChemDiv proposes design and synthesis of heterocyclic scaffolds for DEL:

Vast diversity of heterocyclic scaffolds,

Proprietary and continuously validated reactions and library protocols

High Fsp3 scaffolds
  • Flexible and conformationally constrained cores
  • Derivatives and mimics of natural compounds
  • Poly-functional derivatization

Multiple diversity points, ≥ 3

Defined chirality
  • Confirmed relative stereochemistry
  • Confirmed absolute stereochemistry
Protein-Protein Interaction modulation as a focus:
  • Macrocycles
  • Spiro-cycles
  • Natural templates


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