Endocrine

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Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library

33,000 compounds

PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.

GPCR Targeted Library

40,000 compounds

Small-molecule compounds that can be used in GPCR drug discovery. Dysregulation of these receptors causes diabetes, CNS disorders.

Histone Deacetylases (HDAC) Targeted Library

9,500 compounds

Set of small-molecule HDAC inhibitors. HDAC regulate gene expression and its inhibitors act against cancers, neurodegenerative and inflammatory diseases.

RAR (Nuclear receptors) Ligands Library

6,000 compounds

Set of RAR receptor antagonists. The retinoic acid receptor is a type of nuclear receptor which can also act as a transcription factor.

Receptor protein tyrosine phosphatases

3,900 compounds

RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.

Cysteine Proteases Inhibitors Library

8,000 compounds

Set of small-molecule compounds that can target cysteine proteases and be used in drug development for cancer, viral, infections treatment.

16,000 compounds

Molecules from c-Met Library target receptor tyrosine kinase. It prevents binding hepatocyte growth factor with c-Met which can lead to cancer.

Proline Kinase Library

2,000 compounds

Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.

Androgen Receptor Antagonists Library

4,300 compounds

Androgen Receptor Antagonists Library is a set of non-steroidal small molecules for prostate cancer treatment.

Glucocorticoid receptors Library

5,000 compounds

Glucocorticoid Receptors Library is small-molecule selective modulators of GR which regulates gene transcription.

SH2 PTB Focused Library

7,000 compounds

SH2 PTB domains Focused Library is a set of inhibitors. SH2 and PTB are small protein modules that mediate PPIs involved in signal transduction pathways.

Type II Kinase Inhibitors Library

8,000 compounds

Type II Kinase Inhibitors Library is a set of non-ATP site inhibitors or activators that bind to an extended ATP site including a back pocket.

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