Endocrine

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Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library

33,000 compounds

PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.

Histone Deacetylases (HDAC) Targeted Library

9,500 compounds

It is a set of HDAC inhibitors. HDAC regulate gene expression and its inhibitors act against cancers, neurodegenerative and inflammatory diseases.

Receptor protein tyrosine phosphatases

3,900 compounds

RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.

RAR (Nuclear receptors) Ligands Library

6,000 compounds

Nuclear receptors Ligands Library is a set of RAR receptor antagonists. The retinoic acid receptor is a type of nuclear receptor which can also act as a transcription factor.

Cysteine Proteases Inhibitors Library

8,000 compounds

Cysteine Proteases Inhibitors Library is a set of small-molecule compounds that can be used in drug development for cancer, viral, infections treatment.

GPCR Targeted Library

40,000 compounds

G protein-coupled receptors Targeted Library is small-molecule compounds that can be used in GPCR drug discovery. Dysregulation of these receptors causes diabetes, CNS disorders.

Androgen Receptor Antagonists Library

4,300 compounds

Androgen Receptor Antagonists Library is a set of non-steroidal small-molecules for prostate cancer treatment.

SH2 PTB Focused Library

7,000 compounds

SH2 PTB domains Focused Library is a set of inhibitors. SH2 and PTB are small protein modules that mediate PPIs involved in signal transduction pathways.

Proline Kinase Library

2,000 compounds

Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.

Type II Kinase Inhibitors Library

8,000 compounds

Type II Kinase Inhibitors Library is a set of non-ATP site inhibitors or activators that bind to an extended ATP site including a back pocket.

16,000 compounds

Molecules from c-Met Library target receptor tyrosine kinase. It prevents binding hepatocyte growth factor with c-Met which can lead to cancer.

Glucocorticoid receptors Library

5,000 compounds

Glucocorticoid Receptors Library is small-molecule selective modulators of GR which regulates gene transcription.

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