Endocrine

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Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library

32,596 compounds

PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.

GPCR Targeted Library

29,185 compounds

Small-molecule compounds that can be used in GPCR drug discovery. Dysregulation of these receptors causes diabetes, CNS disorders.

RAR (Nuclear receptors) Ligands Library

6,767 compounds

Set of RAR receptor antagonists. The retinoic acid receptor is a type of nuclear receptor which can also act as a transcription factor.

15,080 compounds

Molecules from c-Met Library target receptor tyrosine kinase. It prevents binding hepatocyte growth factor with c-Met which can lead to cancer.

Histone Deacetylases (HDAC) Targeted Library

9,769 compounds

Set of small-molecule HDAC inhibitors. HDAC regulate gene expression and its inhibitors act against cancers, neurodegenerative and inflammatory diseases.

Cysteine Proteases Inhibitors Library

7,801 compounds

Set of small-molecule compounds that can target cysteine proteases and be used in drug development for cancer, viral, infections treatment.

Receptor protein tyrosine phosphatases

3,765 compounds

RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.

Proline Kinase Library

2,081 compounds

Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.

Androgen Receptor Antagonists Library

4,244 compounds

Androgen Receptor Antagonists Library is a set of non-steroidal small molecules for prostate cancer treatment.

Glucocorticoid receptors Library

4,768 compounds

Glucocorticoid Receptors Library is small-molecule selective modulators of GR which regulates gene transcription.

Type II Kinase Inhibitors Library

6,996 compounds

Type II Kinase Inhibitors Library is a set of non-ATP site inhibitors or activators that bind to an extended ATP site including a back pocket.

SH2 PTB Focused Library

5,886 compounds

SH2 PTB domains Focused Library is a set of inhibitors. SH2 and PTB are small protein modules that mediate PPIs involved in signal transduction pathways.

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