Androgen Receptor Antagonists Library
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Description
The library has been designed around 21 core structures (in fact, this is not limit and more cores can be identified for further library expansion).
Each of these cores is able to provide 1-3 scaffolds, so entire library has been populated around 51 scaffolds.
Total number of populated library members – 14,278
23 scaffolds have been finally selected and prioritized for the library synthesis:
Priority # 1 – 14 scaffolds,
Priority # 2 – 4 scaffolds,
Priority # 3 – 5 scaffolds;
4.3K-members Library around 17 scaffolds has been synthesized.
