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Type II Kinase Inhibitors Library

Type II Kinase Inhibitors Library

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Desirable size of the custom library selection
Number of compounds
Amount
Volume
uL
Description

Type II inhibitors bind to an extended ATP site including a back pocket formed by displacement of highly conserved DFG (Asp-Phe-Gly) motif (‘DFG-out’) at the start of the activation segment of the kinase. This is an inactive conformation.

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