Mimetics
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4400 compounds
Covalent serine binders library, 10 warhead scaffolds 4 400 compounds
1400 compounds
The library contains 1400 compounds that seems to be analogues of approved drugs.
2,292 compounds
Nucleoside Mimetics Library is a set of modified nucleosides that are used as antiviral and antitumor drugs. They were also designed for HIV therapy.
20,000 compounds
microRNAs (miRs) are small (~18e25 nucleotides)
23,943 compounds
Recognition Elements PPI Library includes conformationally constrained analogues of bioactive peptides: gamma-, beta-turns, dipeptide mimetics.
23,722 compounds
PPI Tripeptide Mimetics Library is small-molecule PPI inhibitors that mimic significant endogenous tripeptides.
68,388 compounds
PPI Helix Turn 3D Mimetics Library was designed on sp3-enriched scaffolds that mimic key recognition elements of protein secondary structure.
2,679 compounds
Small-molecule compounds that mimic the action of protein and modulates PPI.
36,711 compounds
Small molecules that mimic the action of peptides thus modulating PPI. Protein secondary structures are targets for mimicry.
19,079 compounds
Library contains nonpeptide small-molecules that inhibit PPI. They are structural mimetics to target proteins.
4200 compounds
The use of covalently binding inhibitors is steadily growing, with numerous molecules progressing through the stages of clinical trials and even make it to become marketed drugs.
24,737 compounds
Alpha-Helix Mimetics Library is a set of peptidomimetics. Alpha-helices are key recognition elements of protein secondary structure.
29,000 compounds
RNA Isosteric Trinucleotide Mimetics is small molecules targeting RNA expansion repeats. Trinucleotide repeats overexpression causes various disorders.
1,503 compounds
3D Mimetics PPI Library is a set of small-molecule compounds that mimic key recognition elements of protein secondary structure.
Tags
Custom ChemistryNovel Scaffolds and Discovery LibrariesCustom Building Blocks for DNA Encoded LibrariesScale up SynthesisMacrocycle CompoundsIn silico Drug Design (CADD)PROTACADME, DMPKMedicinal ChemistryDNA Encoded Libraries-CDI-CapabilitiesDiscovery BiologyAssay DevelopmentHigh Throughput Screening (HTS)Animal ModelsToxicology and SafetyChemistry, Manufacturing and ControlsPre-Plated SetRepresentative CompoundsNatural-Product3D-PharmacophoreMCE-18RepresentativeSoluble DiversityTargeted DiversitySmartTMAntiviralGPCR3DPhenotypic ScreeningCNS activityTranscription FactorsDrugs LibraryTarget ActivityTherapeutical DiversityCNSIon ChannelsProteases HumanKinases HumanPhosphatases HumanReceptors HumanOpportunistic PathogensCancerCardiovascularMetabolicImmune systemInfectionsMusculoskeletalDigestive systemRespiratory tractOtorhinolaryngologicNervous systemEyeMaleFemaleHemic and lymphaticCongenitalSkinEndocrineAnimalWoundsKinasesProteasesPhosphatasesNuclear receptorsOthersPPI modulatorsReceptor's ligandsEpigeneticMimeticsCyclic compoundsFragmentsPoolChemical classes AgroAllosteric Inhibitors