Nervous system

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Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library

33,000 compounds

PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.

Neurotransmitter Transporter Inhibitors Library

12,000 compounds

Neurotransmitter Transporter Inhibitors Library is a set of small-molecule inhibitors. They are used to treat mental disorders.

Ion Channels Focused Library

26,000 compounds

Ion Channels Focused Library is small-molecule compounds selected for modulating ion channels proteins. They are therapeutic targets of CNS diseases.

GPCR Targeted Library

40,000 compounds

Small-molecule compounds that can be used in GPCR drug discovery. Dysregulation of these receptors causes diabetes, CNS disorders.

Histone Deacetylases (HDAC) Targeted Library

9,500 compounds

Set of small-molecule HDAC inhibitors. HDAC regulate gene expression and its inhibitors act against cancers, neurodegenerative and inflammatory diseases.

RNA Isosteric Trinucleotide Mimetics Library

29,000 compounds

RNA Isosteric Trinucleotide Mimetics is small molecules targeting RNA expansion repeats. Trinucleotide repeats overexpression causes various disorders.

Protein Kinases Inhibitors Library

38,000 compounds

Protein Kinases Inhibitors Library is modulators that are used in cancer and inflammation treatment.

Receptor protein tyrosine phosphatases

3,900 compounds

RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.

Cysteine Proteases Inhibitors Library

8,000 compounds

Set of small-molecule compounds that can target cysteine proteases and be used in drug development for cancer, viral, infections treatment.

Ligand-Gated Ion Channels Library

4,000 compounds

Ligand-Gated Ion Channels Library is a set of small-molecule compounds that target LGICs. They can be used in the treatment of neurodegenerative disorders.

Proline Kinase Library

2,000 compounds

Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.

Purine Based Nucleoside Mimetics Library

1,300 compounds

Purine Based Nucleoside Mimetics Library is nucleoside analogues that mimic metabolic purines. They are extracellular messengers and endogenous modulators.

Purinergic Library

3,500 compounds

Purinergic Library is a set of purinergic receptor antagonists. Such antagonists is used for thrombosis and stroke treatment.

Autophagy-Targeted Library

17,000 compounds

Autophagy-Targeted Library is a set of small-molecule modulators for the regulation of autophagy.

Adenosine Receptors Targeted Library

21,000 compounds

Adenosine Receptors Targeted Library is a set of small-molecule ligands. They can be used for treating neurodegeneration diseases.

Epitranscriptome Focused Small Molecule Library

21,000 compounds

Epitranscriptome Focused Small Molecule Library modulates the activity of proteins involving in aberrant RNA modification.

Glucocorticoid receptors Library

5,000 compounds

Glucocorticoid Receptors Library is small-molecule selective modulators of GR which regulates gene transcription.

Integrin Receptors Targeted library

2,000 compounds

Integrin Receptors Targeted library is a set of RGD peptides or peptidomimetics that affect many events in tumor cells thereby directly induce apoptosis.

CNS MPO Library

30,000 compounds

CNS MPO Library is a set of drug-likeness designed via Multi-Parameter Optimization for improved BBB-permeability.

Nucleic Acid Ligands

9,000 compounds

Nucleic Acid Ligands is a set of minor and major groove DNA or RNA binders. Such small molecules have proven to be effective antiviral and cancer agents.

26,000 compounds

CNS library is a unique set of small molecule compounds for protein targets relevant for the CNS therapeutic area and neurological related diseases.

CNS BBB Library

23,000 compounds

CNS BBB Library is a set of blood-brain barrier permeable compounds with high chemical diversity and novelty of structures.

Neuropeptide S Library

3,000 compounds

Neuropeptide S Library is a set of small-molecule NPSR ligands. They can be used in psychiatric disorders treatment as anxiolytics and analgesics.

Voltage-Gated Ion Channel-Targeted Library

5,000 compounds

Voltage-Gated Ion Channel-Targeted set is small molecule compounds that contribute to treating pain.

44,000 compounds

CNS Targets Library is a set of small-molecule compounds acting on various CNS targets.

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