Nervous system

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Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library

33,000 compounds

PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.

Histone Deacetylases (HDAC) Targeted Library

9,500 compounds

It is a set of HDAC inhibitors. HDAC regulate gene expression and its inhibitors act against cancers, neurodegenerative and inflammatory diseases.

Protein Kinases Inhibitors Library

38,000 compounds

Protein Kinases Inhibitors Library is modulators that are used in cancer and inflammation treatment.

RNA Isosteric Trinucleotide Mimetics Library

29,000 compounds

RNA Isosteric Trinucleotide Mimetics is small molecules targeting RNA expansion repeats. Trinucleotide repeats overexpression causes various disorders.

Ion Channels Focused Library

26,000 compounds

Ion Channels Focused Library is small-molecule compounds selected for modulating ion channels proteins. They are therapeutic targets of CNS diseases.

Purine Based Nucleoside Mimetics Library

1,300 compounds

Purine Based Nucleoside Mimetics Library is nucleoside analogues that mimic metabolic purines. They are extracellular messengers and endogenous modulators.

Receptor protein tyrosine phosphatases

3,900 compounds

RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.

Cysteine Proteases Inhibitors Library

8,000 compounds

Cysteine Proteases Inhibitors Library is a set of small-molecule compounds that can be used in drug development for cancer, viral, infections treatment.

GPCR Targeted Library

40,000 compounds

G protein-coupled receptors Targeted Library is small-molecule compounds that can be used in GPCR drug discovery. Dysregulation of these receptors causes diabetes, CNS disorders.

Neurotransmitter Transporter Inhibitors library

12,000 compounds

Neurotransmitter Transporter Inhibitors Library is a set of reuptake inhibitors. They are used to treat mental disorders.

CNS BBB Library

23,000 compounds

CNS BBB Library is a set of blood-brain barrier permeable compounds with high chemical diversity and novelty of structures.

CNS MPO Library

30,000 compounds

CNS MPO Library is a set of drug-likeness designed via Multi-Parameter Optimization for improved BBB-permeability.

Purinergic Library

3,500 compounds

Purinergic Library is a set of purinergic receptor antagonists. Purinergic signaling is mediated by ATP. Such antagonists is used for thrombosis treatment.

Proline Kinase Library

2,000 compounds

Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.

Epitranscriptome Focused Small Molecule Library

21,000 compounds

Epitranscriptome Focused Small Molecule Library modulates the activity of proteins involving in aberrant RNA modification.

Adenosine Receptors Targeted Library

21,000 compounds

Adenosine Receptors Targeted Library is a set of small-molecule ligands. They can be used for treating neurodegeneration diseases.

Ligand-Gated Ion Channels Library

4,000 compounds

Ligand-Gated Ion Channels Library is a set of small-molecule compounds that target LGICs. They can be used in the treatment of neurodegenerative disorders.

Integrin Receptors Targeted library

2,000 compounds

Integrin Receptors Targeted library is a set of RGD peptides or peptidomimetics that affect many events in tumor cells thereby directly induce apoptosis.

Autophagy-Targeted Library

17,000 compounds

Autophagy-Targeted Library is a set of small-molecule modulators for the regulation of autophagy.

26,000 compounds

CNS library is a unique set of small molecule compounds for protein targets relevant for the CNS therapeutic area and neurological related diseases.

Glucocorticoid receptors Library

5,000 compounds

Glucocorticoid Receptors Library is small-molecule selective modulators of GR which regulates gene transcription.

Voltage-Gated Ion Channel-Targeted Library

5,000 compounds

Voltage-Gated Ion Channel-Targeted set is small molecule compounds that contribute to treating pain.

Nucleic Acid Ligands

9,000 compounds

Nucleic Acid Ligands is a set of minor and major groove DNA or RNA binders. Such small molecules have proven to be effective antiviral and cancer agents.

Neuropeptide S Library

3,000 compounds

Neuropeptide S Library is a set of small-molecule NPSR ligands. They can be used in psychiatric disorders treatment as anxiolytics and analgesics.

44,000 compounds

CNS Targets Library is a set of small-molecule compounds acting on various CNS targets.

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