Therapeutical areas

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ACE2 Library

3,051 compounds

Angiotensin-converting enzyme Library is a set of small-molecule inhibitors of the SARS-CoV-2 binding site.

Neurotransmitter Transporter Inhibitors Library

10,813 compounds

Neurotransmitter Transporter Inhibitors Library is a set of small-molecule inhibitors. They are used to treat mental disorders.

Antiviral HBV Library

9,726 compounds

Antiviral HBV Library is a set of non-nucleoside compounds for HBV treatment.

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library

32,596 compounds

PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.

Protein Kinases Inhibitors Library

36,324 compounds

Protein Kinases Inhibitors Library is modulators that are used in cancer and inflammation treatment.

GPCR Targeted Library

29,185 compounds

Small-molecule compounds that can be used in GPCR drug discovery. Dysregulation of these receptors causes diabetes, CNS disorders.

CORONAVIRUS Library

20,750 compounds

Coronavirus Library (COVID-19) is a set of small-molecule compounds that prevent coronaviral binding and further replication.

Antiviral Library

65,937 compounds

Antiviral Library is a set of small-molecule antiviral agents. These inhibitors target a wide range of viral proteins.

DGK Inhibitors Library

10,674 compounds

Diacylglycerol kinase Inhibitors Library is a set of small-molecules that can inhibit the progression of cancer and innate cytotoxic immunocytes.

NOTUM (Wnt signaling) Library

4,003 compounds

Small molecules that can inhibit NOTUM thus potentially treating diseases caused by dysregulation of Wnt signaling.

Carbonic Anhydrase II Library

5,000 compounds

Carbonic anhydrase II library is a set of compounds belonging to the sulfonamides, mercaptans and phenols aimed at modulating of Carbonic anhydrase II activity

RNA Isosteric Trinucleotide Mimetics Library

28,544 compounds

RNA Isosteric Trinucleotide Mimetics is small molecules targeting RNA expansion repeats. Trinucleotide repeats overexpression causes various disorders.

RAR (Nuclear receptors) Ligands Library

6,767 compounds

Set of RAR receptor antagonists. The retinoic acid receptor is a type of nuclear receptor which can also act as a transcription factor.

Ion Channels Focused Library

26,421 compounds

Ion Channels Focused Library is small-molecule compounds selected for modulating ion channels proteins. They are therapeutic targets of CNS diseases.

Ligand-Gated Ion Channels Library

3,743 compounds

Ligand-Gated Ion Channels Library is a set of small-molecule compounds that target LGICs. They can be used in the treatment of neurodegenerative disorders.

Antibacterial Compounds Library

13,658 compounds

Antibacterial Compounds Library is a set small-molecule inhibitors of bacterial vital proteins.

C-Met Library

15,080 compounds

Molecules from c-Met Library target receptor tyrosine kinase. It prevents binding hepatocyte growth factor with c-Met which can lead to cancer.

Akt-Targeted Library

15,000 compounds

Akt Targeted Library is a set of small-molecule inhibitors of the Akt-signaling network. These inhibitors are widely used in cancer treatment.

Arginase Targeted Library

2,016 compounds

Arginase Targeted Library is a set of small-molecule compounds against arginase. This enzyme is implicated in cancer immunosuppression and tumor growth.

Nucleoside Mimetics Library

2,292 compounds

Nucleoside Mimetics Library is a set of modified nucleosides that are used as antiviral and antitumor drugs. They were also designed for HIV therapy.

Histone Deacetylases (HDAC) Targeted Library

9,769 compounds

Set of small-molecule HDAC inhibitors. HDAC regulate gene expression and its inhibitors act against cancers, neurodegenerative and inflammatory diseases.

Serine Proteases Inhibitors Library

31,972 compounds

Serine Proteases Inhibitors Library is a set of small-molecule compounds that target serine proteases and can be used in anticancer drug discovery.

Protein Arginine Methyltransferases Library

27,102 compounds

PRMT Library is set of small-molecule compounds with reported affinity against cancer-assosiated PRMTs.

Cysteine Proteases Inhibitors Library

7,801 compounds

Set of small-molecule compounds that can target cysteine proteases and be used in drug development for cancer, viral, infections treatment.

3CLpro Library

4,792 compounds

3-chymotrypsin-like protease Library is a set of small-molecule compounds for inhibiting coronavirus replication.

Receptor protein tyrosine phosphatases

3,765 compounds

RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.

PI3K-Targeted Library

16,720 compounds

PI3K-Targeted Library is a set of small-molecule inhibitors of PI3K signaling pathway. They can be used in effective inhibiting tumor progression.

Proline Kinase Library

2,081 compounds

Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.

Androgen Receptor Antagonists Library

4,244 compounds

Androgen Receptor Antagonists Library is a set of non-steroidal small molecules for prostate cancer treatment.

Aurora A-B Kinases Targeted Library

9,342 compounds

Set of small-molecule serine/threonine kinases family inhibitors.

KRAS-Targeted Library

16,000 compounds

KRAS-Targeted Library is a set of novel KRAS-active compounds.

PD-1/L1 Library

491 compounds

PD-1/L1 Library is a set of PD-1 and PD-L1 inhibitors. It is a group of anticancer drugs that block the activity of immune checkpoint proteins.

Glucocorticoid receptors Library

4,768 compounds

Glucocorticoid Receptors Library is small-molecule selective modulators of GR which regulates gene transcription.

PLpro Library

6,354 compounds

Papain-like protease Library is a set of drug-like compounds for COVID-19. They inhibit viral replication and the dysregulation of signaling cascades in infected cells.

Autophagy-Targeted Library

4,550 compounds

Autophagy-Targeted Library is a set of small-molecule modulators for the regulation of autophagy.

Bromodomain Modulators Library

5,430 compounds

Bromodomain Modulators Library is a set of drug-like compounds aimed at modulating PPI of bromodomain-containing proteins with other vital proteins.

Epitranscriptome Focused Small Molecule Library

20,989 compounds

Epitranscriptome Focused Small Molecule Library modulates the activity of proteins involving in aberrant RNA modification.

MEF2-HDAC (class II) Modulators Library

4,805 compounds

MEF2-HDAC (class II) Modulators Library is a set of drug-like compounds aimed at modulating PPI of MEF2 with HDAC involved in physiological processes.

GABA Library

7,123 compounds

Set of GABA receptor antagonists. These drug-like compounds inhibit the action of GABA and produce stimulant and convulsant effects.

Purinergic Library

3,271 compounds

Purinergic Library is a set of purinergic receptor antagonists. Such antagonists are used for thrombosis and stroke treatment.

Adenosine Receptors Targeted Library

19,626 compounds

Adenosine Receptors Targeted Library is a set of small-molecule ligands. They can be used for treating neurodegeneration diseases.

Regenerative Medicine Focused Library

23,032 compounds

Regenerative Medicine Focused Library is a chemical space that includes promoters of regeneration. They help to repair diseased organs or tissues.

Antimitotic Tubulin Library

17,182 compounds

Antimitotic Tubulin Library is a set of small-molecule tubulin binders. These inhibitors are potential antimitotic drugs for anticancer therapy.

TLR-8 ligands Library

597 compounds

TLR-8 Ligands Library is a set of small-molecule TLR-8 agonists. They can be used in adjuvantation research and for the treatment of ovarian cancer.

Developmental Pathway (Hh/Wnt) Set

2,230 compounds

Developmental Pathway Hh/Wnt Set is inhibitors of the Hedgehog and Wnt-signaling pathways implicated in cancer.

Purine Based Nucleoside Mimetics Library

1,156 compounds

Purine Based Nucleoside Mimetics Library is nucleoside analogues that mimic metabolic purines. They are extracellular messengers and endogenous modulators.

Antifungal Library

16,046 compounds

Antifungal Library is a set of small-molecule compounds that target fungi proteins and can be used in antifungal drug development.

Allosteric Kinases Inhibitors Library

22,697 compounds

Small‐molecule allosteric kinase modulators that target allosteric pockets of kinases outside the conserved ATP‐binding pocket.

Type II Kinase Inhibitors Library

6,996 compounds

Type II Kinase Inhibitors Library is a set of non-ATP site inhibitors or activators that bind to an extended ATP site including a back pocket.

Antiparasite Library

23,762 compounds

Antiparasite Library is a set of small-molecule compounds for drug discovery. It consists of antibacterial, antifungal and insecticide chemicals.

Steroid-like Compounds

498 compounds

Steroid-like compounds library is steroid-based molecules that regulate biological function. These synthetic steroids can treat inflammation.

Lipid Metabolism Library

9,149 compounds

Lipid Metabolism Library is a set of small-molecule modulators of proteins involved in lipid metabolism.

MDM2-p53 interaction inhibitors Library

21,144 compounds

MDM2-p53 Interaction Inhibitors Library is a set of drug-like compounds aimed at modulating PPI of MDM2 with p53 involved in tumorigenesis.

CNS MPO Library

28,284 compounds

CNS MPO Library is a set of drug-likeness designed via Multi-Parameter Optimization for improved BBB-permeability.

SH2 PTB Focused Library

5,886 compounds

SH2 PTB domains Focused Library is a set of inhibitors. SH2 and PTB are small protein modules that mediate PPIs involved in signal transduction pathways.

Hsp90-Targeted Library

10,991 compounds

Heat shock protein 90 Targeted Library is a set of small-molecule modulators that inhibit the activity of HSP90/70 and can be used as anticancer drugs.

MCL1 Targeted Library

12,206 compounds

Set of small-molecule compounds that inhibit MCL1 thus restoring the apoptotic pathway in tumor cells.

Anti-Inflammatory Library

24,162 compounds

Anti-Inflammatory Library is a set of small-molecule compounds that target pivotal proteins and receptors participating in the inflammatory process.

Anticancer Library

61,619 compounds

Anticancer Library is a set of small-molecule compounds with anticancer activity and vast target space.

Anti-HIV1 Library

18,507 compounds

Anti-HIV1 Library is a set of anti-HIV1 small-molecule agents for different viral targets.

Chelators targeting matrix metalloproteinases library

8,600 compounds

Chelators targeting matrix metalloproteinases are small-molecule that inhibit proteolytic activity of tumor cells and prevent metastasis.

Indoleamine 2,3-dioxygenase 1 Focused Library

5,601 compounds

Indoleamine 2,3-dioxygenase1 Focused Library is a set of small-molecule compounds that can inhibit inappropriate IDO activity in tumours.

BRD4 Targeted Library

4,462 compounds

BRD4 Targeted Library is a set of small-molecule compounds that inhibit transcriptional and epigenetic regulator - BRD4.

Integrin Receptors Targeted library

1,708 compounds

Integrin Receptors Targeted library is a set of RGD peptides or peptidomimetics that affect many events in tumor cells thereby directly induce apoptosis.

Inhibitors of beta-Catenin Signaling

6,960 compounds

Inhibitors of beta-Catenin Signaling is small molecules that target PPI of beta-catenin with other proteins involved in significant physiological processes.

Nucleic Acid Ligands

8,118 compounds

Nucleic Acid Ligands is a set of minor and major groove DNA or RNA binders. Such small molecules have proven to be effective antiviral and cancer agents.

Cardiovascular Library

22,203 compounds

Cardiovascular Library is a set of small-molecule compounds with vast target space for cardiovascular disease drug discovery.

Anti-Aging Library

44,952 compounds

Anti-Aging Library is small molecules targeting cellular pathways and biological targets that are implicated in aging.

Anti-infective Library

19,320 compounds

Anti-infective Library is a set of small-molecule compounds against various infectious agents.

Neuropeptide S Library

2,800 compounds

Neuropeptide S Library is a set of small-molecule NPSR ligands. They can be used in psychiatric disorders treatment as anxiolytics and analgesics.

Voltage-Gated Ion Channel-Targeted Library

4,723 compounds

Voltage-Gated Ion Channel-Targeted set is small molecule compounds that contribute to treating pain.

Epigenetics Focused Set

25,883 compounds

Focused Epigenetics Library is a set of small-molecule modulators that target epigenetic proteins.

CNS BBB Library

22,790 compounds

CNS BBB Library is a set of blood-brain barrier permeable compounds with high chemical diversity and novelty of structures.

Bcl2-PPI Inhibitors Library

11,568 compounds

Bcl2 PPI Inhibitors Library is small molecules that inhibit regulators of programmed cell death.

STING Agonist Library

5,939 compounds

STING Agonist Library is small-molecules that bind and activate STING and lead to IFN production. Can be used in cancer immunotherapy.

CNS Library

26,000 compounds

CNS library is a unique set of small molecule compounds for protein targets relevant for the CNS therapeutic area and neurological related diseases.

SH2 Library

10,440 compounds

SH2 Domain Library is a set of inhibitors. SH2 are modular units, which bind to tyrosyl-phosphorylated peptide on their target protein mediating PPI.

Chemokine Receptor-Targeted Library

18,150 compounds

Chemokine Receptor Targeted Library is a set of small-molecule ligands. Modulation of chemokine receptor is used in the treatment of inflammatory diseases.

CNS Targets

44,085 compounds

CNS Targets Library is a set of small-molecule compounds acting on various CNS targets.

Immunological Library

6,531 compounds

Immunological Library is a set of small-molecule compounds that target vast space of proteins involved in immune system.

Macl-GPIb alpha Interaction Library

22,214 compounds

Macl-GPIb alpha set targets leukocyte-platelet interaction. This leads to an antithrombotic effect.

Angiogenesis library

14,449 compounds

Angiogenesis Library is a set of small-molecule compounds that target proteins involved in new blood vessels forming.