Therapeutical areas

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ACE2 Library

3,117 compounds

Angiotensin-converting enzyme Library is a set of small-molecule inhibitors of the SARS-CoV-2 binding site.

CORONAVIRUS Library

21,145 compounds

Coronavirus Library (COVID-19) is a set of small-molecule compounds that prevent coronaviral binding and further replication.

3CLpro Library

4,871 compounds

3-chymotrypsin-like protease Library is a set of small-molecule compounds for inhibiting coronavirus replication.

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library

33,000 compounds

PTPN Targeted Library is a set of small-molecule inhibitors. Protein tyrosine phosphatases are important signaling molecules in cell proliferation.

Histone Deacetylases (HDAC) Targeted Library

9,500 compounds

It is a set of HDAC inhibitors. HDAC regulate gene expression and its inhibitors act against cancers, neurodegenerative and inflammatory diseases.

Bromodomain Modulators Library

5,816 compounds

Bromodomain Modulators Library is a set of drug-like compounds aimed at modulating PPI of bromodomain-containing proteins with other vital proteins.

PLpro Library

6,442 compounds

Papain-like protease Library is a set of drug-like compounds for COVID-19. They inhibit viral replication and the dysregulation of signaling cascades in infected cells.

Lipid Metabolism Library

9,000 compounds

Lipid Metabolism Library is a set of small-molecule modulators of proteins involved in lipid metabolism.

Protein Kinases Inhibitors Library

38,000 compounds

Protein Kinases Inhibitors Library is modulators that are used in cancer and inflammation treatment.

PD-1/L1 Library

500 compounds

PD-1/L1 Library is a set of PD-1 and PD-L1 inhibitors. It is a group of anticancer drugs that block the activity of immune checkpoint proteins.

Nucleoside Mimetics Library

2,600 compounds

Nucleoside Mimetics Library is a set of modified nucleosides that are used as antiviral and antitumor drugs. They were also designed for HIV therapy.

Antiviral HBV Library

11,000 compounds

Antiviral HBV Library is a set of non-nucleoside compounds for HBV treatment.

RNA Isosteric Trinucleotide Mimetics Library

29,000 compounds

RNA Isosteric Trinucleotide Mimetics is small molecules targeting RNA expansion repeats. Trinucleotide repeats overexpression causes various disorders.

Regenerative Medicine Focused Library

23,000 compounds

Regenerative Medicine Focused Library is a chemical space that includes promoters of regeneration. They help to repair diseased organs or tissues.

Ion Channels Focused Library

26,000 compounds

Ion Channels Focused Library is small-molecule compounds selected for modulating ion channels proteins. They are therapeutic targets of CNS diseases.

Antiviral Library

87,043 compounds

Antiviral Library is a set of small-molecule antiviral agents. These inhibitors target a wide range of viral proteins.

Arginase Targeted Library

2,000 compounds

Arginase Targeted Library is a set of small-molecule compounds against arginase. This enzyme is implicated in cancer immunosuppression and tumor growth.

Purine Based Nucleoside Mimetics Library

1,300 compounds

Purine Based Nucleoside Mimetics Library is nucleoside analogues that mimic metabolic purines. They are extracellular messengers and endogenous modulators.

Receptor protein tyrosine phosphatases

3,900 compounds

RPTP Targeted Library is small-molecule inhibitors. Disruption of protein tyrosine phosphorylation contributes to a variety of human diseases.

RAR (Nuclear receptors) Ligands Library

6,000 compounds

Nuclear receptors Ligands Library is a set of RAR receptor antagonists. The retinoic acid receptor is a type of nuclear receptor which can also act as a transcription factor.

Cysteine Proteases Inhibitors Library

8,000 compounds

Cysteine Proteases Inhibitors Library is a set of small-molecule compounds that can be used in drug development for cancer, viral, infections treatment.

GPCR Targeted Library

40,000 compounds

G protein-coupled receptors Targeted Library is small-molecule compounds that can be used in GPCR drug discovery. Dysregulation of these receptors causes diabetes, CNS disorders.

Chelators targeting matrix metalloproteinases library

9,300 compounds

Chelators targeting matrix metalloproteinases are small-molecule that inhibit proteolytic activity of tumor cells and prevent metastasis.

Neurotransmitter Transporter Inhibitors library

12,000 compounds

Neurotransmitter Transporter Inhibitors Library is a set of reuptake inhibitors. They are used to treat mental disorders.

Serine Proteases Inhibitors Library

37,000 compounds

Serine Proteases Inhibitors Library is a set of small-molecule compounds that target serine proteases and can be used in anticancer drug discovery.

CNS BBB Library

23,000 compounds

CNS BBB Library is a set of blood-brain barrier permeable compounds with high chemical diversity and novelty of structures.

MDM2-p53 interaction inhibitors Library

23,000 compounds

MDM2-p53 Interaction Inhibitors Library is a set of drug-like compounds aimed at modulating PPI of MDM2 with p53 involved in tumorigenesis.

Antibacterial Compounds Library

15,000 compounds

Antibacterial Compounds Library is a set small-molecules inhibitors of bacterial vital proteins.

Inhibitors of beta-Catenin Signaling

8,000 compounds

Inhibitors of beta-Catenin Signaling is small molecules that target PPI of beta-catenin with other proteins involved in significant physiological processes.

MCL1 Targeted Library

12,000 compounds

Induced myeloid leukemia cell differentiation protein Targeted Library is a set of small-molecule compounds that inhibit MCL1 thus restoring the apoptotic pathway in tumor cells.

Protein Arginine Methyltransferases Library

31,000 compounds

PRMT Library is set of small-molecule compounds with reported affinity against cancer-assosiated PRMTs.

CNS MPO Library

30,000 compounds

CNS MPO Library is a set of drug-likeness designed via Multi-Parameter Optimization for improved BBB-permeability.

Purinergic Library

3,500 compounds

Purinergic Library is a set of purinergic receptor antagonists. Purinergic signaling is mediated by ATP. Such antagonists is used for thrombosis treatment.

Androgen Receptor Antagonists Library

4,300 compounds

Androgen Receptor Antagonists Library is a set of non-steroidal small-molecules for prostate cancer treatment.

MEF2-HDAC (class II) Modulators Library

6,000 compounds

MEF2-HDAC (class II) Modulators Library is a set of drug-like compounds aimed at modulating PPI of MEF2 with HDAC involved in physiological processes.

SH2 PTB Focused Library

7,000 compounds

SH2 PTB domains Focused Library is a set of inhibitors. SH2 and PTB are small protein modules that mediate PPIs involved in signal transduction pathways.

Proline Kinase Library

2,000 compounds

Proline Kinase Library is a set of kinase inhibitors. These kinases play a crucial role in diverse cellular processes and human diseases.

Epitranscriptome Focused Small Molecule Library

21,000 compounds

Epitranscriptome Focused Small Molecule Library modulates the activity of proteins involving in aberrant RNA modification.

Adenosine Receptors Targeted Library

21,000 compounds

Adenosine Receptors Targeted Library is a set of small-molecule ligands. They can be used for treating neurodegeneration diseases.

PI3K-Targeted Library

19,000 compounds

PI3K-Targeted Library is a set of small-molecule inhibitors of PI3K signaling pathway. They can be used in effective inhibiting tumor progression.

Immunological Library

7,300 compounds

Immunological Library is a set of small-molecule compounds that target vast space of proteins involved in immune system.

Allosteric Kinases Inhibitors Library

26,000 compounds

Small‐molecule allosteric kinase inhibitors bind to an allosteric site outside the conserved ATP‐binding pocket overcoming poor selectivity of kinase inhibitors.

Type II Kinase Inhibitors Library

8,000 compounds

Type II Kinase Inhibitors Library is a set of non-ATP site inhibitors or activators that bind to an extended ATP site including a back pocket.

Akt-Targeted Library

12,000 compounds

Akt Targeted Library is a set of small-molecule inhibitors of the Akt-signaling network. These inhibitors are widely used in cancer treatment.

Ligand-Gated Ion Channels Library

4,000 compounds

Ligand-Gated Ion Channels Library is a set of small-molecule compounds that target LGICs. They can be used in the treatment of neurodegenerative disorders.

Anti-HIV1 Library

21,000 compounds

Anti-HIV1 Library is a set of anti-HIV1 small-molecule agents for different viral targets.

Steroid-like-compounds

543 compounds

Steroid-like compounds library is steroid-based molecules that regulate biological function. These synthetic steroids can treat inflammation.

Integrin Receptors Targeted library

2,000 compounds

Integrin Receptors Targeted library is a set of RGD peptides or peptidomimetics that affect many events in tumor cells thereby directly induce apoptosis.

STING Agonist Library

6,000 compounds

STING Agonist Library is small-molecules that bind and activate STING and lead to IFN production. Can be used in cancer immunotherapy.

C-Met Library

16,000 compounds

Molecules from c-Met Library target receptor tyrosine kinase. It prevents binding hepatocyte growth factor with c-Met which can lead to cancer.

KRAS-Targeted Library

11,000 compounds

KRAS-Targeted Library is a set of novel KRAS-active compounds. The small G-proteins KRas function as GDP–GTP regulated binary switches in many signal transduction pathways.

Developmental Pathway (Hh/Wnt) Set

2,000 compounds

Developmental Pathway Hh/Wnt Set is inhibitors of the Hedgehog and Wnt-signaling pathways implicated in cancer.

Bcl2-PPI Inhibitors Library

11,000 compounds

Bcl2 PPI Inhibitors Library is small molecules that inhibit regulators of programmed cell death.

Anticancer Library

65,000 compounds

Anticancer Library is a set of small-molecule compounds with anticancer activity and vast target space.

Autophagy-Targeted Library

17,000 compounds

Autophagy-Targeted Library is a set of small-molecule modulators for the regulation of autophagy.

Antimitotic Tubulin Library

18,000 compounds

Antimitotic Tubulin Library is a set of small-molecule tubulin binders. These inhibitors are potential antimitotic drugs for anticancer therapy.

GABA library

7,271 compounds

gamma-Aminobutyric acid Library is a set of GABAA receptor antagonists. These drug-like compounds inhibit the action of GABA and produce stimulant and convulsant effects.

CNS Library

26,000 compounds

CNS library is a unique set of small molecule compounds for protein targets relevant for the CNS therapeutic area and neurological related diseases.

Glucocorticoid receptors Library

5,000 compounds

Glucocorticoid Receptors Library is small-molecule selective modulators of GR which regulates gene transcription.

Aurora A-B Kinases Library

10,000 compounds

Aurora A-B Kinases Library is a set of small-molecule serine/threonine kinases family inhibitors. Overexpression of Aurora kinases is clarified in a number of cancers.

DGK Inhibitors Library

12,000 compounds

Diacylglycerol kinase Inhibitors Library is a set of small-molecules that can inhibit the progression of cancer and innate cytotoxic immunocytes.

SH2 Library

12,000 compounds

SH2 Domain Library is a set of inhibitors. SH2 are modular units, which bind to tyrosyl-phosphorylated peptide on their target protein mediating PPI.

Voltage-Gated Ion Channel-Targeted Library

5,000 compounds

Voltage-Gated Ion Channel-Targeted set is small molecule compounds that contribute to treating pain.

Nucleic Acid Ligands

9,000 compounds

Nucleic Acid Ligands is a set of minor and major groove DNA or RNA binders. Such small molecules have proven to be effective antiviral and cancer agents.

TLR-8 ligands Library

900 compounds

TLR-8 Ligands Library is a set of small-molecule TLR-8 agonists. They can be used in adjuvantation research and for the treatment of ovarian cancer.

Epigenetics Focused Set

30,431 compounds

Focused Epigenetics Library is a set of small-molecule modulators that target epigenetic proteins.

Anti-Aging Library

50,000 compounds

Anti-Aging Library is small molecules targeting cellular pathways and biological targets that are implicated in aging.

Antifungal Library

16,824 compounds

Antifungal Library is a set of small-molecule compounds that target fungi proteins and can be used in antifungal drug development.

BRD4 Targeted Library

5,000 compounds

BRD4 Targeted Library is a set of small-molecule compounds that inhibit transcriptional and epigenetic regulator - BRD4.

Indoleamine 2,3-dioxygenase 1 Focused Library

6,000 compounds

Indoleamine 2,3-dioxygenase1 Focused Library is a set of small-molecule compounds that can inhibit inappropriate IDO activity in tumours.

Hsp90-Targeted Library

13,000 compounds

Heat shock protein 90 Targeted Library is a set of small-molecule modulators that inhibit the activity of HSP90/70 and can be used as anticancer drugs.

Anti-infective Library

20,600 compounds

Anti-infective Library is a set of small-molecule compounds against various infectious agents.

Neuropeptide S Library

3,000 compounds

Neuropeptide S Library is a set of small-molecule NPSR ligands. They can be used in psychiatric disorders treatment as anxiolytics and analgesics.

Chemokine Receptor-Targeted Library

20,000 compounds

Chemokine Receptor Targeted Library is a set of small-molecule ligands. Modulation of chemokine receptor is used in the treatment of inflammatory diseases.

Antiparasite Library

25,376 compounds

Antiparasite Library is a set of small-molecule compounds for drug discovery. It consists of antibacterial, antifungal and insecticide chemicals.

CNS Targets

44,000 compounds

CNS Targets Library is a set of small-molecule compounds acting on various CNS targets.

Anti-Inflammatory Library

28,000 compounds

Anti-Inflammatory Library is a set of small-molecule compounds that target pivotal proteins and receptors participating in the inflammatory process.

Cardiovascular Library

23,000 compounds

Cardiovascular Library is a set of small-molecule compounds with vast target space for cardiovascular disease drug discovery.

Macl-GPIb alpha Interaction Library

27,000 compounds

Macl-GPIb alpha set targets leukocyte-platelet interaction. This leads to an antithrombotic effect.

Angiogenesis library

17,000 compounds

Angiogenesis Library is a set of small-molecule compounds that target proteins involved in new blood vessels forming.